Yale University  ·  Department of Biomedical Engineering

Statistical physics for high‑dimensional biology.

We use statistical physics to understand the complexity of biological systems, with a focus on emergent low dimensionality and the role of non-equilibrium processes.

Selected work

Recent papers and preprints

All publications →

Lab news

What's happening

Papers, preprints, talks, and people.

August 2026
Karthik is at the NITMB spin glass workshop in Chicago, on high-dimensional landscapes in biology.
2026
Brooke's paper is accepted at Cell Reports Physical Sciences, on declining communication fidelity in aging.
2026
Jeremy's paper is accepted at Physical Review Research, on endocytosis shaping extracellular gradients.
2026
Karthik's paper is accepted at PRX Life, on low-dimensional coexistence in microbial ecosystems.
December 2025
Andrew's directional sensing paper is out in PNAS. Receptor degradation plus diffusion is enough to give a eukaryotic cell a sense of direction.

Openings

Come work with us

We look for people who enjoy sitting between physics, statistics, and biology, and who are willing to learn whichever of the three they know least. Graduate students apply through Yale BME or the BBS program. Postdoc and undergraduate inquiries are welcome any time.